MODAPLEX Platform

Simplify molecular precision testing

Modern management of complex disease, like in oncology and cancer care, relies heavily on biomarker testing for diagnosis, selection of effective therapies, and treatment monitoring. As the number of actionable biomarkers continues to increase, serial single-gene testing has become less practical due to its large specimen requirements, long turnaround times, and cost- & labor-intensive bioinformatic data analysis. There is a rising need for more advanced technologies enabling multi-gene testing as a new standard of care. A multi-gene testing approach helps to ensure capturing all relevant biomarkers at once, making the most of limited sample tissue while also decreasing critical turnaround times.

Despite the overwhelming need for multi-gene and multi-biomarker testing, many clinicians and pathologists rely on outsourcing this service to specialized reference laboratories, leading to long turnaround times for results, and potentially suboptimal treatment decisions. The MODAPLEX platform automates multi-gene testing into a consolidated workflow with turn-around times of 4 hours. This allows hospitals, clinics, and molecular pathologies to bring this valuable technology in-house, facilitating faster results and better coordination of care.

The MODAPLEX platform is a benchtop system for molecular profiling and comprehensive multi-marker testing. With little hands-on time and a simple workflow, up to 48 reactions can be processed with 4 hours turn-around time. Detection, differentiation, and if needed quantification of all clinically relevant genetic alterations can be consolidated onto one platform. That makes MODAPLEX ideal for multi-gene testing and analysis of biomarker signatures.

MODAPLEX is available as closed system with a defined assay portfolio, as well as an enabling platform to customers interested in developing and commercializing their multi-marker assays of interest.

PCR Setup

15-50 min
5

MODAPLEX Run

3 h
5

Data Analysis

10 min

4 h

The MODAPLEX load-and-walk-away workflow is identical for all tests and combinations of tests. The workflow comprises three steps: PCR set-up, Modaplex run, and data analysis. Results are evaluated with the MODAPLEX Result Analyzer (MODAPLEX Reporter) software. MODAPLEX Reporter provides automatic import of acquired data from the MODAPLEX device, along with the analysis and summary of results in a comprehensive report.

PCR Setup

15-50 min
3

MODAPLEX Run

3 h
3

Data Analysis

10 min

4 h

The MODAPLEX load-and-walk-away workflow is identical for all tests and combinations of tests. The workflow comprises three steps: PCR set-up, Modaplex run, and data analysis. Results are evaluated with the MODAPLEX Result Analyzer (MODAPLEX Reporter) software. MODAPLEX Reporter provides automatic import of acquired data from the MODAPLEX device, along with the analysis and summary of results in a comprehensive report.

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Contact

BIOTYPE GmbH

Moritzburger Weg 67
01109 Dresden
Germany

Mail: modaplex@biotype.de

Tel: +49 351 8838 400

© 2023 BIOTYPE GmbH